<div dir="ltr"><p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;text-align:justify;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial;font-size:11pt;font-family:Calibri,sans-serif"><b><span style="font-size:12pt;font-family:"Times New Roman",serif">Data/Horário:</span></b><span style="font-size:12pt;font-family:"Times New Roman",serif"> </span><span style="font-size:12pt;font-family:"Times New Roman",serif;color:red">20/09, 8h – Online (inglês)</span><span style="font-size:12pt;font-family:"Times New Roman",serif"></span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;text-align:justify;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial;font-size:11pt;font-family:Calibri,sans-serif"><b><span style="font-size:12pt;font-family:"Times New Roman",serif">Palestrante: </span></b><span style="font-size:12pt;font-family:"Times New Roman",serif">Chris Brien
(University of Adelaide, Australia)</span><b><span style="font-size:12pt;font-family:"Times New Roman",serif"></span></b></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;text-align:justify;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial;font-size:11pt;font-family:Calibri,sans-serif"><b><span style="font-size:12pt;font-family:"Times New Roman",serif">Title:</span></b><span style="font-size:12pt;font-family:"Times New Roman",serif"> The design
and analysis of a two-phase experiments involving human subjects: a case study</span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;text-align:justify;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial;font-size:11pt;font-family:Calibri,sans-serif"><b><span style="font-size:12pt;font-family:"Times New Roman",serif">Summary</span></b><span style="font-size:12pt;font-family:"Times New Roman",serif"> </span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;text-align:justify;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-size:12pt;font-family:"Times New Roman",serif">Two-phase experiments were introduced
in 1952 by the Australian statistician George McIntyre. Their use has been most
prevalent in agriculture experiments, especially plant breeding experiments.
However, there is the potential for their application to be much more
widespread. This potential is not being realized because of a lack of awareness
of multiphase experiments within the statistical community. A potted history of
two-phase experiments will be given and an explanation of what constitutes a
two-phase experiment provided, using a scenario in a sports Science context as
an introductory example. The use of the anatomy of a design for understanding
the confounding in the experiment will be outlined. The case study involves a
pain-rating experiment reported in a 1997 paper by Solomon, Prkachin, &amp;
Farewell. The data from a subset of the experiment was analyzed by Farewell and
Herberg (2003) and by Jarrett, Farewell and Herzberg (2020) using
analyses-of-variance and linear mixed models. A further re-analysis using
linear mixed models that has been described by Brien (2022) will be outlined.
Suggested improvements for the design of future similar experiments, based on
the results of the re-analysis, will also be presented.</span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;text-align:justify;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial;font-size:11pt;font-family:Calibri,sans-serif"><b><span style="font-size:12pt;font-family:"Times New Roman",serif">References</span></b></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;text-align:justify;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-size:12pt;font-family:"Times New Roman",serif">Brien, C. J. (2022). Designing,
understanding and modelling two-phase experiments with human subjects.
Statistical Methods in Medical Research, 31(4), 626-645.</span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;text-align:justify;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-size:12pt;font-family:"Times New Roman",serif">Farewell, V. T.; Herzberg, A. M.
(2003). Plaid designs for the evaluation of training for medical practitioners.
Journal of Applied Statistics, 30(9), 957-965.</span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;text-align:justify;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-size:12pt;font-family:"Times New Roman",serif">Jarrett, R. G., Farewell, V. T.;
Herzberg, A. M. (2020). Random effects models for complex designs. Statistical
Methods in Medical Research, 29(12), 3695-3706.</span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;text-align:justify;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-size:12pt;font-family:"Times New Roman",serif">Solomon, P. E., Prkachin, K. M.;
Farewell, V. (1997). Enhancing sensitivity to facial expression of pain. Pain,
71(3), 279-284.</span></p><p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;text-align:justify;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-size:12pt;font-family:"Times New Roman",serif"><br></span></p><p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;text-align:justify;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-size:12pt;font-family:"Times New Roman",serif">Para os interessados, segue a programação (quase) completa.</span></p><p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;text-align:justify;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-size:12pt;font-family:"Times New Roman",serif">Se alguém tiver interesse, escreva-me para que eu mande o link</span></p><p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;text-align:justify;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-size:12pt;font-family:"Times New Roman",serif">(aqueles que não receberam ainda).</span></p><p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;text-align:justify;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-size:12pt;font-family:"Times New Roman",serif"><br></span></p><p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;text-align:justify;line-height:normal;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-size:12pt;font-family:"Times New Roman",serif">Saudações, Clarice</span></p><div><br></div></div>