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<p><span lang="EN-US">Link: <a href="https://zoom.us/j/95781336030">https://zoom.us/j/95781336030</a></span></p><p><span lang="EN-US"><span style="color:rgb(0,0,0);font-family:Verdana,sans-serif;font-size:14px">Dia: 06 de abril de 2023</span></span></p><p><span lang="EN-US"><span style="color:rgb(0,0,0);font-family:Verdana,sans-serif;font-size:14px">Horário: 12h-13h15</span><br></span></p><p><span lang="EN-US"> </span><span></span></p>
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<strong><span lang="EN-US" style="font-family:"Verdana",sans-serif;color:black;font-weight:normal">Title:</span></strong><b><span lang="EN-US" style="font-family:"Verdana",sans-serif;color:black"> </span></b><b><span lang="EN-US" style="font-family:"Verdana",sans-serif">Sparse
 precision matrix estimation in phenotypic trait evolution models</span></b><b><span lang="EN-US" style="font-family:"Verdana",sans-serif;color:black"></span></b></p>
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<p style="line-height:18.0pt"><strong><span lang="EN-US" style="font-family:"Verdana",sans-serif;color:black">Speaker:</span></strong><span lang="EN-US" style="font-family:"Verdana",sans-serif;color:black"> 
<a href="https://orcid.org/0000-0002-2791-6735" target="_blank">Gabriela Cybis</a> </span></p>
<p style="line-height:18.0pt"><strong><span lang="EN-US" style="font-family:"Verdana",sans-serif;color:black">University:</span></strong><span lang="EN-US" style="font-family:"Verdana",sans-serif;color:black"> 
<a href="http://www.ufrgs.br/ufrgs/inicial" target="_blank">UFRGS</a></span></p>
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<p style="text-align:justify;line-height:115%"><strong><span lang="EN-US" style="font-family:"Verdana",sans-serif;color:#414042"> </span></strong></p>
<p style="text-align:justify;line-height:115%"><strong><span lang="EN-US" style="font-family:"Verdana",sans-serif">Abstract:</span></strong><span lang="EN-US" style="font-family:"Verdana",sans-serif;color:#414042"> </span><span lang="EN-US" style="font-family:"Verdana",sans-serif">
</span><span lang="EN-US" style="font-size:11.5pt;line-height:115%;font-family:"Verdana",sans-serif">Phylogenetic trait evolution models allow for the estimation of evolutionary correlations between a set of traits observed in a sample of related organisms.
 By directly modeling the evolution of the traits along an estimable phylogenetic tree, the model's structure effectively controls for shared evolutionary history. In these models, relevant correlations are usually assessed through the high posterior density
 interval of their marginal distributions. However, the selected correlations alone may not provide the full picture regarding trait relationships. Their association structure, expressed through a graph that encodes partial correlations, can in contrast highlight
 sparsity patterns featuring direct associations between traits. In order to develop a model-based method to identify this association structure we explore the use of Gaussian graphical models (GGM) for covariance selection. We model the precision matrix with
 a G-Wishart conjugate prior, which results in sparse precision estimates. Furthermore, the model naturally allows for Bayes Factor tests of association between the traits, with no additional computation required. We evaluate our approach through Monte Carlo
 simulations and applications that examine the association structure and evolutionary correlations of phenotypic traits in Darwin's finches and genomic and phenotypic traits in prokaryotes. Our approach provides accurate graph estimates and lower errors for
 the precision and correlation parameter estimates, particularly for conditionally independent traits, which are the target for sparsity in GGMs.</span><span lang="EN-US"></span></p>
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<p><span style="font-size:10.5pt;font-family:"Verdana",sans-serif;color:black">April 6, 2023</span></p>
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<p><span style="font-size:10.5pt;font-family:"Verdana",sans-serif;color:black">12pm de São Paulo, Brasil (UTC/GMT -03:00)</span></p>
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<p><span style="font-size:8.5pt;font-family:"Verdana",sans-serif;color:#3a3a41">Rua Quatá, 300 - Vila Olímpia - São Paulo/SP - Brasil - CEP: 04546-042 | Tel: (11) 4504-2400</span><span></span></p>
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</div></div><br clear="all"><div><br></div><span class="gmail_signature_prefix">-- </span><br><div dir="ltr" class="gmail_signature" data-smartmail="gmail_signature"><div dir="ltr"><span style="color:rgb(0,0,0);font-family:Calibri,Arial,Helvetica,sans-serif,"Apple Color Emoji","Segoe UI Emoji",NotoColorEmoji,"Segoe UI Symbol","Android Emoji",EmojiSymbols;font-size:small">Hedibert Freitas Lopes, PhD</span><br style="color:rgb(0,0,0);font-family:Calibri,Arial,Helvetica,sans-serif,"Apple Color Emoji","Segoe UI Emoji",NotoColorEmoji,"Segoe UI Symbol","Android Emoji",EmojiSymbols;font-size:small"><span style="color:rgb(0,0,0);font-family:Calibri,Arial,Helvetica,sans-serif,"Apple Color Emoji","Segoe UI Emoji",NotoColorEmoji,"Segoe UI Symbol","Android Emoji",EmojiSymbols;font-size:small">Professor of Statistics and Econometrics</span><br style="color:rgb(0,0,0);font-family:Calibri,Arial,Helvetica,sans-serif,"Apple Color Emoji","Segoe UI Emoji",NotoColorEmoji,"Segoe UI Symbol","Android Emoji",EmojiSymbols;font-size:small"><span style="color:rgb(0,0,0);font-family:Calibri,Arial,Helvetica,sans-serif,"Apple Color Emoji","Segoe UI Emoji",NotoColorEmoji,"Segoe UI Symbol","Android Emoji",EmojiSymbols;font-size:small">INSPER - Institute of Education and Research</span><br style="color:rgb(0,0,0);font-family:Calibri,Arial,Helvetica,sans-serif,"Apple Color Emoji","Segoe UI Emoji",NotoColorEmoji,"Segoe UI Symbol","Android Emoji",EmojiSymbols;font-size:small"><span style="color:rgb(0,0,0);font-family:Calibri,Arial,Helvetica,sans-serif,"Apple Color Emoji","Segoe UI Emoji",NotoColorEmoji,"Segoe UI Symbol","Android Emoji",EmojiSymbols;font-size:small">Rua Quatá, 300 - São Paulo, SP 04546-042 Brazil</span><br style="color:rgb(0,0,0);font-family:Calibri,Arial,Helvetica,sans-serif,"Apple Color Emoji","Segoe UI Emoji",NotoColorEmoji,"Segoe UI Symbol","Android Emoji",EmojiSymbols;font-size:small"><span style="color:rgb(0,0,0);font-family:Calibri,Arial,Helvetica,sans-serif,"Apple Color Emoji","Segoe UI Emoji",NotoColorEmoji,"Segoe UI Symbol","Android Emoji",EmojiSymbols;font-size:small">Phone: +55 11 4504-2343</span><br style="color:rgb(0,0,0);font-family:Calibri,Arial,Helvetica,sans-serif,"Apple Color Emoji","Segoe UI Emoji",NotoColorEmoji,"Segoe UI Symbol","Android Emoji",EmojiSymbols;font-size:small"><span style="color:rgb(0,0,0);font-family:Calibri,Arial,Helvetica,sans-serif,"Apple Color Emoji","Segoe UI Emoji",NotoColorEmoji,"Segoe UI Symbol","Android Emoji",EmojiSymbols;font-size:small"><a href="http://www.hedibert.org" target="_blank">www.hedibert.org</a></span><br></div></div></div>