<div dir="ltr"><p class="MsoNormal" style="text-align:justify"><b><span lang="PT-BR" style="font-size:10pt;font-family:Arial,sans-serif;background-image:initial;background-repeat:initial">Seminário - Projeto Temático: Modelos de
Regressão e Aplicações</span></b></p>

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<p class="MsoNormal" style="text-align:justify"><b><span lang="EN-US" style="font-size:10pt;font-family:Arial,sans-serif;background-image:initial;background-repeat:initial">Título: </span></b><span lang="EN-US" style="font-size:9.5pt;font-family:Arial,sans-serif;background-image:initial;background-repeat:initial">An EM Algorithm for
Estimating the Destructive Weighted Poisson Cure Rate Model</span><b><span lang="EN-US" style="font-size:10pt;font-family:Arial,sans-serif;background-image:initial;background-repeat:initial"></span></b></p>

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<p class="MsoNormal" style="text-align:justify"><b><span style="font-size:10pt;font-family:Arial,sans-serif;background-image:initial;background-repeat:initial">Palestrante: </span></b><span style="font-size:9.5pt;font-family:Arial,sans-serif;background-image:initial;background-repeat:initial">Diego I. Gallardo Mateluna</span><span style="font-size:10pt;font-family:Arial,sans-serif;background-image:initial;background-repeat:initial"> , IME-USP</span><span style="font-size:10pt;font-family:Arial,sans-serif;background-image:initial;background-repeat:initial"></span></p>

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<p class="MsoNormal" style="text-align:justify"><b><span lang="PT-BR" style="font-size:10pt;font-family:Arial,sans-serif;background-image:initial;background-repeat:initial">Quando: </span></b><span lang="PT-BR" style="font-size:10pt;font-family:Arial,sans-serif;background-image:initial;background-repeat:initial">2 de outubro, sexta-feira, às 11h.</span></p>

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<p class="MsoNormal" style="text-align:justify"><b><span lang="PT-BR" style="font-size:10pt;font-family:Arial,sans-serif;background-image:initial;background-repeat:initial">Onde: </span></b><span lang="PT-BR" style="font-size:10pt;font-family:Arial,sans-serif;background-image:initial;background-repeat:initial">Auditório Jacy Monteiro, Bloco B, piso térreo
- IME-USP</span></p>

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<p class="MsoNormal" style="text-align:justify;background-image:initial;background-repeat:initial"><b><span lang="PT-BR" style="font-size:9.5pt;font-family:Arial,sans-serif">Resumo</span></b><span lang="PT-BR" style="font-size:9.5pt;font-family:Arial,sans-serif">. </span><span lang="EN-US" style="font-size:9.5pt;font-family:Arial,sans-serif">In
this work, an EM algorithm is developed to compute estimates for parameters in
destructive weighted Poisson cure rate models. It is shown, analytically, the
advantage of the procedure with respect to the maximization of the observed
likelihood function. The approach allows a simple implementation of different
distributions for time-to-event of non-destroyed concurrent causes. The
performance of the method is evaluated through simulation studies and by
analysing a real data set related to patients with malignant melanoma.</span></p>

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<p class="MsoNormal" style="background-image:initial;background-repeat:initial"><span style="font-size:9.5pt;font-family:Arial,sans-serif">Joint work with Heleno Bolfarine and Antonio Carlos
Pedroso de Lima.</span></p>

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